Free Statistical Significance of Study Essay Sample
To determine the effect of the drug, the total number of those who were infected after taking the drug was compared with the total number of those who were infected among the group which was put on a placebo. The percentage of risk reduction after using the drug was calculated from the difference between the total number of those infected after taking the drug and those who were infected after taking the placebo. Randomization was done in assigning the study subjects in five countries in order to minimize bias in the sample and enhance the significance of the study. Case follow ups was also done on those involved in the study to establish if there was compliance in taking the drugs as well as monitoring the side effects of the drug.
Based on the study findings, it was concluded that the total chance of risk reduction for infection with HIV among gay men who took Truvada was 44%. The study also established that the risk of infection also depends on the drug's compliance rate with those who are compliant registering a 90% less risk of infection. From this study, it was also established that the drug's compliance rate among the subjects was very poor among those who were given the drug with only 3 out of 34 found to have taken the drug. These findings suggest that the results were not appropriate as there was a very low compliance rate which makes it hard to determine whether the results obtained for those who took the drug were purely as a result of the drug or due to chance. Due to the failure to control the study in a manner that minimizes the limitations like poor compliance and dishonest as well as failure to repeat the treatments on the same subjects or a different sample, the findings of the study are not statistically significant at the statistically acceptable confidence levels.